Webteins. Free ISG15 is detected as both extracellular and intracellular protein. The mature form of ISG15 contains two ubiquitin-like domains with a calculated molecular weight of 17 … Web5 mag 2024 · ISG15 silencing enhances the production of IFN-α/β in C3A cells. To investigate the levels of IFN-α/β when ISG15 was inhibited, we first constructed three …
(PDF) Interferon-stimulated Gene 15 (ISG15) is a trigger for ...
WebJeon YJ, et al. ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway. EMBO Rep. 2009 Apr;10 (4):374-80. Product Sheets: (by Lot #): H2666-9a.pdf Research Areas : Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Invasion/Metastasis, Metabolic Disorder Web6 mar 2009 · Coexpression of ISG15 led to a marked decrease in the activation of JNK in M2 cells complemented with c-filamin B, but not in c-K2467R-complemented cells , … how heavy are the dumbbells you lift pfp
ISG15 inhibits cancer cell growth and promotes apoptosis
Web26 nov 2024 · IFN-stimulated gene 15 (ISG15), a ubiquitin-like molecule, is strongly up-regulated by type I interferon as a crucial response to a variety of microbial and cellular stress stimuli. However, the role of ISG15 in colon cancer remains unclear. Web6 ago 2014 · ISG15 silencing inhibits tumor growth, angiogenesis and prolongs tumor-bearing mice lifespan (A, B) Effect of ISG15 on HCC tumor growth in xenografted tumor models (**, P < 0.01). ... Jeon YJ, Yoo HM, Chung CH. ISG15 and immune diseases. Biochimica et biophysica acta. Web5 mag 2011 · The biological role of ISG15 is strongly associated with the modulation of cell immune function, and there is mounting evidence suggesting that many viral pathogens evade the host innate immune … highest scoring baseball game 2021